Free Webinar On: Advances in Compound Identification Using Metabolomics

Genetic Engineering & Biotechnology News Presents an Informative and Educational Streaming Audio Webinar
Advances in Compound Identification Using Metabolomics

Broadcast Date: Wednesday, September 23, 2009 Time: 1:00 pm EDT
The metabolome can be looked at as a summation of genomic, proteomic, as well as environmental influences and has thus become a rich source of unbiased, real-time information on gene function. Even though there are less metabolites than genes and proteins, their chemical diversity and wide range of concentrations present formidable challenges to analysis. This free webinar explores state-of-the-art mass spectrometry and MS/MS techniques for routine and novel identification of biomarkers and drug targets through metabolomics.
Who should attend?
Systems biologists
Academic and industrial biomarker investigators
Drug discovery scientists involved in target identification
Cell biologists in the pharmaceutical or biopharmaceutical industries
Mass spectroscopists working in life science laboratories
Key Learning Points
Use of high-resolution LC/MS and other techniques for de novo chemical structure determination
Application of Metlin and the Metlin MS/MS library, which contain more than 23,000 endogenous, exogenous, and theoretical metabolites, for identification of metabolites and complete unknowns
The typical metabolomics work flow as well as the need for and purpose of compound identification in metabolomics research
Sample analysis tips and tricks as well as MS and MS/MS data interpretation
Speakers include Paul R. West, Ph.D., Director, BioAnalytical Chemistry, Stemina Biomarker Discovery; Gary Siuzdak, Ph.D., Senior Director, Scripps Center for Mass Spectrometry;and Steven Fischer, Senior Applications Chemist, Agilent Technologies. Your host for this webinar will be John Sterling, Editor in Chief of Genetic Engineering & Biotechnology News.
A live Q&A session will follow the presentations, offering you a chance to pose questions to our expert panelists. For more about this webinar, click here.

2009 International Symposium on Bioelectronics and Bioinformatics-RMIT UNIVERSITY AUSTRALIA

university is planning for international symposium in field of BIOINFORMAICS-
The Symposium will provide a forum for researchers, engineers, and research students to discuss and disseminate the latest research progresses in the areas of biomedical engineering, micro and nano electronics, e-health, bioinformatics, and bio-signal processing.Call for papers closes on August 31.
Event details
Event:
2009 International Symposium on Bioelectronics and Bioinformatics (ISBB2009)
Person:
RMIT Research
Date:
December 09, 2009December 11, 2009
Time:
TBA
Location:
School of Electrical and Computer Engineering,RMIT City Campus,Melbourne, Australia
2009 International Symposium on Bioelectronics and Bioinformatics (ISBB2009) will be held in the great city of Melbourne, Australia from 9-11 December, 2009 jointly organised by RMIT University, Australia and Heterogeneous Integration Consortium, Taiwan, ROC.
We have witnessed the rapid development of bioelectronics as well as bioinformatics in last decade. ISBB2009 will provide a forum for researchers, engineers, and research students to discuss and disseminate the latest research progresses in the areas of biomedical engineering, micro and nano electronics, e-health, bioinformatics, and bio-signal processing. It will encourage the cross-boundary communication and collaboration between scientists and engineers who aim to develop state-of-the-art practical solutions for addressing real word biomedicine and health problems.
Call for papers
The ISBB2009 organisation committee is inviting you to submit original unpublished technical research papers describing latest work in, but not limited to, the following areas:
Implantable Electronics
VLSI IC Design for Biomedical Application
BioMEMS and Biosensor
Wireless Body Sensor Network
Ambulatory Monitoring System
Bionic Ear and Bionic Eye Development
Diagnostic and Neurosignal Processing
Medical Data Integration and E-health Solutions
Proteomics and Macromolecule Modeling
Biological Signal Processing and Data Mining
All submitted papers will be peer reviewed and the accepted and presented papers will be included in the symposium proceedings as well as the IEEE Xplore. It is requested that full paper submissions not exceeding 4 pages (or approximately 2000 words). It is expected that sufficient technical details will be presented in the paper. Authors should follow the IEEE EMBC paper style to prepare the manuscripts.
Important Dates
May 18
Paper Submission Open
August 31
Paper Submission Due
September 30
Notification to Authors
October 15
Author Registration and Camera-Ready Papers Due
December 9-11
Conference Dates
General Inquiries
For more information:
Visit the 2009 International Symposium on Bioelectronics and Bioinformatics website
Enquiries can be made directly to secretariat@isbb2009.wmah.org

Leadership Role: Stem Cell Research - Pioneering Stem Cell Research Company

A leading stem cell company in India, focusing on Research, Therapeutics and Therapy in the field of regenerative medicine. Their goal is to bring out stem cell based drugs in the near future using Mesenchymal Stem Cells. To develop drugs to treat various diseases, they work on cutting edge research to acquire knowledge & understanding of stem cells and their differentiation process.

They are seeking an experienced senior research scientist with good industry back ground to head the entire research activities. He/She will Leadership Role in the Research function of the Organisation. He/She will be responsible for the overall research and development functions of the company. Responsibilities include innovation in stem cells research towards product development, relating research to business, overseeing the creation, development, design and implementation of the organization’s Stem Cell R&D programs, building partnerships and relationships with the global scientific community, actively contributing toproduct development projects and clinical trials, ensuring good productivity from the scientific team and managing R&D budgets.
Interface within the Organization: Business Heads, Corporate Head HR, Vice Chancellor - University, CEO/COO of Hospitals, Clinical Doctors.
Outside The Organization: Regulatory bodies (DCGI, ICMR etc), Scientific bodies, Biotech Corps, International Stem Cell committees, Research Institutes, Universities, CROs.
Job Description:
1) List the critical accountabilities that must be achieved in order that the job purpose is fulfilled.2) To develop & execute short and long term research and innovation strategies to realize stem cells market potential in local and international markets.3) Design and deliver strategies for “Bench to Bedside” approach in bringing the outcome of applied research to launch novel drugs for clinical applications.4) Develop a team of stem cells experts by setting up supporting education system and obtain research grants in the area of regenerative medicine.5) Enhance scientific value of the organization by filing global patents and publications in peer review and leading scientific journals.6) Develop global and local network with leading scientific bodies to mobilize direct investments in basic and applied research and also improve the company’s image as a leader in stem cell research/therapy
7) Bring in operational excellence in Stem Cell culturing and up scaling. Develop world class stem cell labs with cGMP compliant.8) Develop and leverage Stem Cell platforms for business applications.9) Conduct research and development that creates new products for various ailments.10)Analyze and summarize the results of clinical studies sponsored by the company and partners.11)Create formal reports, white papers and publications of research results.12)Should oversee the infrastructure required for Research & Production.
Candidate Profile:
1) Masters Degree in Biotech / Medicine PhD in relevant field with strong back ground in Stem cells With 5 years experience at a senior level - working in stem cell development or analysis.2) Should have a good Track-record of creating patents, publishing research papers, writing scientific reports and getting outside funding for self-initiated research programs.3) Should have experience in developing Stem Cell based products.4) Should have established record of independent research and critical thinking.5) Should have experience in leading research projects in Stem Cell or related fields.6) Should have Experience in studying Acute Myocardial Infarction, Critical Limb Ischemia, Chronic Obstructive Pulmonary Disease, Liver Cirrhosis, and “Drug Screening & Toxicity” research.
Location: Bangalore
Opportunity ID: SBT-STC5001
Contact Person: Shyam Suryanarayanan: +91-9845094699 or +91-80-65718412

Project fellow vacancy At NIMR Delhi

Two positions of Project Fellows (One based at Delhi and another at DRDE, Gwalior) on a consolidated salary of Rs.10000/-p.m. (No other allowances) are to be filled up on purely temporary, ad hoc and contractual basis under the project titled “Knock down resistance mutation (kdr) in Anopheles culicifacies : frequency distribution in different populations” funded by DRDE,

Gwalior which are coterminous with the project. The maximum tenure of the project is two years. The initial engagement in the posts would be for one year but the period of contract may be curtailed/extended at the discretion of the competent authority.

Interested and eligible candidates may send their bio-data on email admin@mrcindia.org and attend walk-in-interview at above address on 04.09.2009 at 10.00 A.M. along with Bio-data with the photocopies of the testimonials and also originals for verification.

NOC is necessary in the case of persons serving in Central/State Govt./Autonomous Bodies No TA/DA will be paid for attending the interview.
Essential Qualification : First class M.Sc. in Life Sciences/Biotechnology/ Bioinformatics
Desirable : Knowledge of basic Molecular Biology and Bioinformatics tools.
Age : Up to 28 years (Relaxable for SC/ST/OBC candidates as per Govt. rules and also for deserving candidates).

Courtesy
Helpbiotech

Job-Vacancy: Manager At BASF

BASF Plant Science Company GmbH is looking for aBioinformatic Manager (m/f)Essential Requirements:- Bioinformatics expertise with a good overview of the differentfields ofbioinformatics- Sound knowledge of at least one programming language (e.g. Java, C++, C,VB) and scripting abilities (e.g. Perl, Python, shell scripting)- Sound knowledge of biology (doctorate in biology/biochemistry wouldbe a plus)- Knowledge of databases (Oracle, MS SQL Server) and SQL wouldbe beneficial- Experiences in project management would be a benefit- Excellent English skills and working knowledge in German- Work experience in an industrial setting would be a benefit- - Excellent communication skillscontact person:Ms. Michaela Hambsch,phone ++49 621 60-28102Visit for more details:http://www.basf.com/plantsciencePlease apply preferably online underhttp://www.corporate.basf.com/en/karriere or in writing to BASF SE HRdirekt - D 108 D-67056 Ludwigshafen Tel. ++49 621 60-95200Referencecode:J-BPS-51240079Attachment: J-BPS-51240079_Hambsch.pdfcourtesy:Bioplanetjobs.

Postdoctoral position in Theoretical Molecular Biophysics

Postdoctoral position is available in the Theoretical Molecular Biophysics laboratory headed by Dr. Dima Lukatskyin the department of Chemistry at Ben-Gurion University of the Negev.

We are interested in understanding design
principles of protein interaction specificity,design principles of protein-protein and drug-protein interaction networks,
and general principles of biomolecular recognition in a living cell.We invite a highly motivated, recent Ph.D. graduate
in physics, computer science, bioinformatics or chemistry and interested in biophysics and systems biology to join our group.
For further information please contact:
Dr. Dima LukatskyDepartment of ChemistryBen-Gurion University of the Negev, Beer ShevaLukatsky@bgu.ac.ilPh. (office) +972-(0)8-6428-370

Systems Biology Jobs at Center of Systems Biology Iceland

Available Positions:
Postdoctoral Position: Mathematical modeling of human metabolism:
Postdoctoral Position: Development of computational methods for human systems biologyFor more Details Please Visit : http://systemsbiology.is/Jobs

A Quick Guide to Teaching R Programming to Computational Biology Students

A good paper on R.http://www.ploscompbiol.org/article/info:doi%2F10.1371%2Fjournal.pcbi.1000482BySukhbir Singh Rattan.

IIT KHARAGPUR BIOINFO Jrf Vacancy

Applications are invited for the temporary Jrf positions available at IIT Kharagpur.

Qualifications & Experience:

M.Sc. or equivalent in Bioinformatics/Life Science/ Physics /Chemistry/Computer Science or M.Tech. in Bioinformatics / Biotechnology/Computer Science.

Valid GATE/ NET score; Experience in C/C++/PERL/ PYTHON programming language. Knowledge in handling Bioinformatics software will be a plus.

Last Date: 17th sep 2009

For further information plz follow the link:
http://www.iitkgp.ac.in/topfiles/sric_job_details.php?serial=1172

Courtesy
Helpbiotech

Fwd: Various PhD Positions in University of Göttingen

http://www.uni-goettingen.de/en/56673.html

DWLKarnal 4 jrf posts

4 jrf posts are available at the ICAR Haryana.


Qualifications:

Pg degree in bioinformatics and
good handling of bioinformatics tools and softwares ,Knowledge of Linux.

Walk in interview on 17th sep

For further information plz follow the link:
http://dwr.in/images/pdf/bio-interview.pdf

Courtesy
Helpbiotech

Research Fellow / Senior Research Fellow in Microbial Ecology : Sydney, NSW 2007 Australia

Job description:

Research Fellow/Senior Research Fellow in Microbial Ecology (Level B/C)
Plant Functional Biology and Climate Change Cluster (C3)
A position at UTS is one of influence, recognition, reward and work-life balance.The Plant Functional Biology and Climate Change Cluster (C3) brings together a core group of expert plant physiologists, ecologists, biological and physical modellers and specialist remote sensing researchers, with the aim of improving and enhancing predictions about the impacts of climate change on natural ecosystems. Working at multiple scales, from cellular to regional, in forest, coastal and estuarine ecosystems, this unique group’s targeted research approach builds on their internationally recognised work into areas including:
• Understanding the physiological trigger of coral bleaching• Climatic influences on aquatic biodiversity• Vulnerability of Antarctic ecosystems to climate change
We are looking for a microbial ecologist working at the intersection of molecular (genomic/proteomic/biochemical) expression in protist diversity (species or communities) and their functional response to climate change. The person will have a background in molecular microbiology and aquatic ecology. Knowledge of gene regulation, molecular probes, antibodies, quantification of metabolic proteins, protein interactions, bioinformatics, advanced microscopy (live imaging), screening, isolation and culturing are highly advantageous.We would be looking for opportunities where other members of the C3 aquatic team could contribute to your research through a deeper understanding of biogeochemical processes, gas exchange, bioenergetics and ecosystem models of microbial consortia (eg symbiosis, biofilms or pelagic communities).
The appointee will be expected to provide research leadership and build research capacity in this research domain and seek funding from external sources, with support of the Research and Innovation Office. A key requirement for the appointee is to foster international and national links with research groups and with industry, government, professions and community organisations. A very good publication record for the stage in career is critical. Demonstrated experience in working in multi-disciplinary teams is desirable.
Salary range: Level B $73,149 to $86,846 pa.Level C $89,551 to $103,086 pa.The University offers salary packaging plus attractive superannuation.
For further information and to apply visit: http://www.hru.uts.edu.au/jobs/
For more information visit: http://www.nature.com/naturejobs/science/jobs/106610-Research-Fellow-Senior-Research-Fellow-in-Microbial-Ecology

Human-chimp interbreeding challenged

Mutation rates may be explained by differences in female promiscuity

A genetic analysis has called into question the controversial claim that early humans and chimpanzees interbred before splitting into separate species.
"Many evolutionary biologists were pretty sceptical" about the interbreeding scenario, says evolutionary geneticist Soojin Yi of the Georgia Institute of Technology in Atlanta. She argues that her explanation — which stems from promiscuity differences among primate species — is "simpler and hence more likely".
In 2006, David Reich and his colleagues at the Broad Institute in Cambridge, Massachusetts, compared the genomes of humans, chimps and three other primate species, and found that the separation of ancient humans from our closest cousins was more complex than a clean break. The time from the beginning to the completion of human-chimp divergence ranged over more than four million years across different parts of the genome, and the X chromosome seemed youngest of all, they reported in Nature. The authors argued that there were in fact two splits — an initial divide, followed by interbreeding, and then final separation in which only a young X chromosome was retained.
Many researchers took issue with this interpretation, arguing that large ancestral population sizes could explain the wide range in genetic divergence times, so there was no need to invoke a complex speciation process. But these critiques still could not account for the youth of the X chromosome.
Now Yi, together with Daven Presgraves of the University of Rochester in New York, have reanalysed the data and suggest that species differences in the levels of female promiscuity can account for the chromosomal inconsistency. The original hypothesis is "way more of a headache for evolutionary biologists", says Yi. The data "can also be explained very well by well-established ideas in molecular evolution".
Relationships matter
Males competing for mates produce different amounts of sperm depending on the mating habits of the species. Chimps are highly promiscuous, humans less so and gorillas not much at all. As such, male chimps face the stiffest competition, so they have the highest sperm counts and the largest testes of the three species. That means that they also undergo more rounds of sperm cell division and make more DNA copying mistakes, leading to higher mutation rates in males than in females. Reich and others had assumed that all primates had the same mutation bias, but Yi and Presgraves argue that mating relationships should be taken into account.
Because females have two X chromosomes and males have only one, the X spends more of its evolutionary history in females, whereas non-sex chromosomes split their time evenly between each gender. Thus, a male-biased mutation rate will lead to proportionally fewer genetic changes on the X and will seem to be younger when using a molecular clock, even if all the chromosomes diverged at around the same time, the researchers argue. Complex speciation is therefore unlikely to be the cause, they report in an invited opinion article in the October issue of Trends in Ecology & Evolution.
"This elegant and simple explanation will be the last piece of the puzzle," says Hideki Innan, a population geneticist at the Graduate University for Advanced Studies in Kanagawa, Japan.
The X factor
But Reich is not convinced. Yi and Presgraves' model "is an exciting hypothesis, but it simply can't explain the data", he says. Their model predicts that chimps should continue to accumulate more mutations on the autosomes compared to the X chromosome even after the species split. But even when Reich reanalysed 30 times more sequence data than his team considered in the original paper, he could not find any difference between the human and chimp lineages.
What's more, only the double-split scenario could explain why genes shared by humans and gorillas, but not chimps, are found everywhere on the non-sex chromosomes but are largely absent on the X. Complex speciation "remains a far-out hypothesis", admits Reich. "But no one has come up with an alternative explanation for the data that holds water."
Presgraves counters that when he included orang-utan data in the analysis, he found that humans and chimps had similarly strong male-biased mutation rates, so he wouldn't expect differences between the two species. What matters, he says, is that both species are more biased than gorilla, which makes the divergence seem younger than when compared to the older primates. In addition, he says, humans share genes with gorillas — albeit at lower levels — which is consistent with his expectations.
Nicholas Barton, an evolutionary geneticist at the Institute of Science and Technology Austria in Klosterneuburg, says that the new theory has the advantage that it is testable. Researchers can survey more species to confirm whether male-biased mutation rates vary with sperm competition. Reich's idea, however, cannot be disproved.
Indeed, in 2003, Hans Ellegren, an evolutionary biologist at Uppsala University in Sweden, calculated the mutation bias in 31 bird species, and found that those with higher rates of extrapair paternity also had higher male mutation rates.
Yi concedes that she can't definitively invalidate Reich's model. "Proof is very hard to come by in evolution biology, unfortunately," she says.
Source: Nature,28 August 2009

PhD Student : Switzerland, Geneva

Description
A PhD student position is available at a new research laboratory which is a joint endeavor of the Department of Structural Biology and Bioinformatics (DBSB) at the Faculty of Medicine of the Geneva University and of the Swiss Institute of Bioinformatics (ISB).
The research project will form part of the CALIPHO initiative (Computational Analysis and Laboratory Investigation of Proteins of Human Origin), which combines molecular and cellular biological methods, in vivo experiments on model organisms and bioinformatics to decipher the function of the numerous uncharacterized human proteins. The identification of novel biological messengers such as hormones, growth factors or cytokines often represents landmark discoveries, with significant impact for both fundamental and applied science. The recent completion of the annotation of the human proteome by the Swiss-Prot group demonstrated that about 2’000 human proteins are still lacking experimental annotations. Among those, some have the profile of potential biological messengers (small secreted proteins). These candidates will be validated and characterized using a series of in vitro (analysis of expression of the cloned genes) and ex vivo experiments (detection of gene expression in tissue samples), resulting in (i) a first level of characterization for the new proteins and (ii) the development of a reduced and filtered set of candidates, from which a panel of three will be chosen for further characterization, based on assessment of tractability and potential impact. In the final phase of the project, these three carefully chosen proteins will be produced and subjected to more in depth analysis (screening for activity on cells and tissues, structural studies, physiological effects) in an attempt to elucidate their functions. This project should lead to (i) the preliminary characterization of a large panel of secreted proteins of unknown function, (ii) an initial assessment of the utility of using a systematic approach, indicating which areas require optimization, and (iii) the in-depth characterization of 1-3 new human secreted biological messengers.

Requirements
Master 2 in biology or biochemistry or equivalent diploma.
Further information (job start, deadline, adress) on:http://www.myscience.ch/en/jobs_and_careers/id5303

Opening for post-doc at University of Munster, Munster, Germany

Project descriptionThis project includes collaboration with experimentalists in the endeavour to extract common principles of host-parasite co-evolution, arguably the major driving force of evolution. Post-holders will apply a wide range of bioinformatics techniques to elucidate molecular details of interactions between hosts and parasites and changes in genomic architecture of either organism. The project requires the analysis of Selexa/454/ABI data, ESTs, genomic data, automated extraction information from literature and making information accessible to the consortium of the SPP1399. Candidates are expected to interact closely with e.g. the MPI for Evolutionary Biology in Ploen, the IFM-Geomar in Kiel and of course groups at the IEB. The project is funded by the German Science Foundation and coordinated jointly by Profs. Erich Bornberg-Bauer and Joachim Kurtz (both IEB, University of Muenster) as well as Hinrich Schulenburg and Thorsten Reusch (both University of Kiel). Postdoctoral and PhD positions are usually paid according to the TVL scheme. Teaching and/or administrative contributions are generally very low, with amount and balance depending on the particular project as well as background, qualifications and experience of candidates. Further information on the Institute, Muenster and the SPP: http://ieb.uni-muenster.de/ http://www.muenster.de/en/ http://ieb.uni-muenster.de/spp/ Required qualifications: * PhD in natural sciences such as biochemistry, biology or biophysics and research experience in bioinformatics OR * PhD in computer science, statistics or bioinformatics with experience and/or desire to excel in a biological area * Good knowledge of biological databases, bioinformatics programmes and scripting languages such as python, perl or ruby is essential. * Motivation and proven ability to carry out research independently * Good communication skills, fluency in English Contact Information University of Muenster Institute for Evolution and Biodiversity Prof Erich Bornberg-Bauer ebb@uni-muenster.de Tel. Number: +40-251-83-21630 http://ieb.uni-muenster.de/bioinf/positions How To Apply: Interested candidates should send applications to Prof. Bornberg-Bauer ebb@uni-muenster.de as pdf attachment (max. 2 pages) detailing: education + degrees with dates, posts held, list of peer reviewed publications, 2-3 names of potential referees and a short statement of research interest or as letter to: Prof. Dr. Erich Bornberg-Bauer Institut for Evolution and Biodiversity, Westfälische Wilhelms Universität Münster Hüfferstrasse 1, D-48149 Münster, Germany www.uni-muenster.de/Evolution.ebb CLOSING DATE is September 30th 2009.

Post-doc position at IMP-Research Institute of Molecular Pathology, Vienna, Austria

A postdoctoral position localized at the IMP in collaboration with Boehringer Ingelheim Oncology in Vienna is available immediately. Research: The person will work closely with scientists at the IMP and Boehringer Ingelheim to implement analysis pipelines for next generation sequencing projects in the area of cancer genomics. In-house generated data as well as selected public domain data sets should be integrated with an already existing large data collection. A strong focus will be the comprehensive characterization of cancer cell lines with the aim to explain and understand genotype-dependent differential responses to novel targeted therapies. Requirements: The successful candidate should have a PhD degree in bioinformatics, molecular biology or in a related discipline with a proven record in genome/transcriptome sequence analysis, preferentially in the context of NGS. A profound understanding of cancer genomics/biology and the ability to translate and communicate results is highly desired. The candidate should be comfortable in handling very large datasets and be able to identify and implement computationally efficient data processing strategies in a linux environment. Terms and locale: The position is initially for two years, location Vienna, Austria. Institution Background: The Research Institute of Molecular Pathology (IMP) is a basic biomedical research institute sponsored largely by Boehringer Ingelheim, as well as research grants from national and international funding agencies. Boehringer Ingelheim is a research-driven international pharmaceutical company with around 40.000 employees world-wide. The research site in Vienna is solely dedicated to cancer research. Links: http://www.imp.ac.at/ http://www.boehringer-ingelheim.com/corporate/research/centres.asp#3 Contact: Interested candidates should contact Christian.Haslinger@boehringer-ingelheim.com along with copies of their CV, publication list and names of reference persons.

Simple Tips Reading Papers and Leading a Discussion about a Paper

In the link pasted below given are some simple, yet important, tips on reading research papers and leading a discussion about the same:http://ocw.mit.edu/NR/rdonlyres/Biology/7-89Fall-2007/Readings/paper_tips.pdf

NLM post-doc fellowships in Computational Bioscience, University of Colorado Denver School of Medicine, USA

The Computational Bioscience Program at the University of Colorado, Denver School of Medicine is recruiting to fill two NLM (NIH) funded postdoctoral fellowships. The Computational Bioscience Program is home to seven core faculty working in the areas of genomics, text mining, molecular evolution, phylogenetics, network analysis, statistical methods, microarray, biomedical ontology, and other areas. The School of Medicine is home to a broad array of outstanding research and instrumentation, including a 900 MHz NMR, extensive DNA sequencing and microarray facilities, and more. We are housed on the first all-new medical campus of the 21st century, close to both the urban amenities of Denver and the beautiful Rocky Mountains. For more information, please consult http://compbio.uchsc.edu SALARY/BENEFITS: Successful candidates will be offered the NRSA specified stipend (based on years of experience), medical insurance, $2000 per year in travel support and $6500 per year in additional research-related expenses. Candidates must have a Ph.D. degree in Computational Biology or a related discipline, and must be U.S. Citizens or Permanent Residents. Contact Information University of Colorado Denver School of Medicine Computational Bioscience Program Kathy Thomas Kathy.R.Thomas@ucdenver.edu Tel. Number: 303-724-3399 FAX Number: 303-324-0355 http://compbio.uchsc.edu How To Apply: Email your CV and arrange for three letters of recommendation. We are looking to fill this slot by October 1, 2009, but will continue the search until an ideal candidate is found.

Post-doc position, Virginia Tech, Blacksburg, USA

A post-doctorate position in Computational Biology is immediately available at Virginia Polytechnic Institute (Virginia Tech), Department of Computer Science. The projects can be any or a combination of work on evolutionary/comparative genomics, phylogenetics, data mining of disease association studies, network biology, and algorithm and software development for large-scale sequence analysis. Excellent opportunities for collaborative research exist within the department’s Bioinformatics group and other academic departments and the Virginia Bioinformatics Institute (VBI) at Virginia Tech. The start date is flexible. Applicants should submit a curriculum vitae and a brief summary of current research and future research interests. Applicants should also arrange for three letters of recommendation to be sent to Dr. Liqing Zhang (lqzhang@vt.edu). The candidates should have a PhD in either (1) molecular evolution, (2) population genetics, (3) algorithms or data mining with bioinformatics experience, or a related field, and a strong computational background.

2 post-doc positions, Vanderbilt University, Nashville, USA

Two postdoctoral positions are available immediately to join the Vanderbilt Microarray Shared Resource (VMSR, http://array.mc.vanderbilt.edu/). The VMSR is currently under expansion and in the transition to Functional Genomics Shared Resource (FGSR). The successful candidates are expected to join the Informatics Group which includes bioinformatics engineers and post-doctoral fellows and is under the leadership of Dr. Zhongming Zhao, Chief Bioinformatics Officer in Vanderbilt-Ingram Cancer Center. The candidates will perform advanced analysis of the data generated from the collaborative projects in FGSR. Currently, data generated and analyzed by VMSR has been published in many high profiling journals including Nature series and Science. The positions are supported by the Vanderbilt-Ingram Cancer Center and NIH grants. The qualified candidates should be highly motivated and have a Ph.D. in bioinformatics, computational biology, molecular biology, or related when the job starts. The successful candidates should have experience in analyzing high-throughput genomic data derived from microarray and some other high throughput technologies (e.g., GWAS, CNVs) and proved skills in at least one programming language (Perl, Java, or C/C++). Good understanding of molecular biology and familiarity with biostatistics are desirable. Applicants should send a CV, brief statement of research interests, and reference to: Zhongming Zhao (zhongming.zhao@vanderbilt.edu
), Chief Bioinformatics Officer, Vanderbilt-Ingram Cancer Center. Please specify the position “Bioinformatics Postdoc in FGSR” in the application.

workshop on Bioinformatics and chemoinformatics

The Department of Biotechnology and Bioinformatics in Christ College, Rajkot is organizing two nationallevel workshops on "Bioinformatics" and "Cheminformatics" during 3rd week ofSeptember, 2009. Three days are set part for each workshop. The workshop onBioinformatics is from September 14 to 16, 2009 and the workshop onCheminformatics is from September 17 to 19, 2009
Further details are put up on the college website:www.christcollegera jkot.edu. in/biciworkshop. html--

INCOB 2009 singapore

We are attending INCOB 2009 ,Singapore starting form 6th September to 11th September . we request people who are attending INCOB 2009 can contact us so that we can share plans, ideas and thoughts . Hope to see your replies . This mail is behalf of Ranganath G - rnathg@gmail.comChirag Matkar - chirag.matkar@gmail.comAs RSG group members will meet any of members attending the conference

MOTIF'09 - A National Level Symposium on Bioinformatics held @ Bharathiar University, on 17th September 2009 -reg.,

A National Level Symposium on Bioinformatics "MOTIF ' 09" is planned to be held on coming 17th at Bharathiar University, Coimbatore. Every one is invited.
Chair speakers of this symposium are
Dr. M. Karthikeyan, National chemical laboratory, Pune ( Lecture Topic: Chemoinformatics & its application in drug discovery & High performance computing)
Dr. Renu Vyas, Dr. D. Y. Patil Biotechnology & Bioinformatics Institute, Akurdi. ( Lecture Topic : Computational Biology & Pharmacophore)
Dr. Mugasimangalam C. Raja, Genotypic Technology, Bangalore. ( Lecture Topic : Next generation Sequencing Technology & the new Revolution in Biology).
Events
Paper Presentation
Topics (for both students and Academician)
Super computing
Artificial intelligence
Functional genomics
Evolutionary model building
Metabolic computing
Bio Cybernetics
Structural biology
Systems biology
Computational Biology
Biomedical informatics
Computational epigenetics
Clinomics
Cheminformatics
Current scenario in research in the field of bioinformatics
Abstract should be submitted on or before 7th September to invitee09@bumotif.info. Selected papers will be informed. Abstract should be in single page form,font style- Times new Roman, font size- 14, Line spacing-1.5 and should not exceed not more than 250 words. 2 persons per Paper, Time Duration:10 minutes ( Presentation - 7 Minutes, Discussion - 3 minutes).
Protein Sudoku (Individual Event, Duration: Half-an-hour)
Bio-Film Quiz (Related to IT & Lief Science, 2 persons per team, Prelims will be conducted)
JAM (Just A Minute, Topics will be given on the spot).
Registration Details
Important Dates
Registration date starts from : 20th August 2009Abstract submission last date : 7th September 2009 Registration deadline : 10th September 2009Selected abstract announcing date : 10th September 2009
Registration
Academician*(Institutional Base)Individual Participation (only Paper and Poster Presentation) - Rs 350Group participation (Minimum 3 participants) - Rs 800
Corporates* Individual - Rs 500
College wise participation** (Rolling trophy will be given for winning college)Per college 10 minimum participants - Rs 2500 Individual Participants - Rs 300
DD should be drawn in favour of MOTIF’09 payable at Coimbatore. The amount paid is not refundable.
* Certificate for Academician and Corporates will vary ** College wise participation must have participated all kind of events.
Contact us
Enquiry Registration and Sponsors- 09944060724Events - 09092465971Accommodation: 09092465972
Mailing Address:
BioInsilicans
Department of Bioinformatics
Bharathiar University
Coimbatore - 641 046
E mail ID : invitee09@bumotif.info, mail@bumotif.info, motifinvitee09@gmail.com
Registration form is enclosed in this email.
For more details visit the webpage - http://www.bumotif.info/index.html
For downloading the application form - http://www.bumotif.info/Registration%20form.pdf

Position at Unit of Animal Genomics @ University of Liège

The Unit of Animal Genomics (UAG) searches candidates (with or without PhDthesis) to join a multidisciplinary team on a two year project funded bythe Walloon region in collaboration with the Walloon Breeders Association.The objective of the project is to prepare Genomic Selection in BelgianBlue beef cattle. Genomic Selection is used to predict breeding values forimportant traits such as growth, carcass quality, etc. based onapproximately 60000 SNP. These predictions are then used for selectionpurposes. For this project, approximately 300 young bulls from anexperimental station will be genotyped per year. Several phenotypes such asgrowth, feed intake, conformation, and carcass are recorded at theexperimental station. It is planned to add more phenotypes to theexperiment. The project involves collaboration with the experimentalstation for phenotype recording, genotyping and statistical analyses of theexperiment.The UAG(http://www.fmv.ulg.ac.be/genmol/Department/Molecular_Genetics/Molecular_Genetics.htm) is part of the Faculty of Veterinary Medecine (University ofLiege) and is localized in the GIGA (http://www.giga.ulg.ac.be) in theSart-Tilman.Candidates can send their CV to Tom Druet (tom.druet@ulg.ac.be / +32 4 36691 72) and Michel Georges (
michel.georges@ulg.ac.be). The position opens onfirst October 2009.~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-o NRSP8 National Animal Genome Project - Sponsored by USDA/CSREES-o WEB: http://www.animalgenome.org/

A postdoctoral position in biological network analysis at the Technion, Israel

A postdoctoral position in biological network analysis at the TechnionA postdoctoral position is available with Tomer Shlomi in the Department ofComputer Science at the Technion. The focus of the group is the developmentof computational methods for modeling the function of large-scale biologicalnetworks, with a special focus on metabolic networks. Potential researchareas for a position include modeling human tissue-specific metabolism,modeling metabolic alterations due to in-born errors of metabolism andcancer, method development for metabolic network reconstruction, andmetabolic, signaling and regulatory network integration. Research projectswill be closely aligned with the interests of the successful candidates.The ideal candidate will be enthusiastic, highly motivated, will have both astrong background in computer science and background/interest in modelingcomplex biological systems, and will have a strong record of accomplishmentin research. The starting date is flexible and can be as early as Oct 2009.Interested applicants should send a PDF with CV, a brief description ofresearch interests and experience, and contact information for threereferences to tomersh@cs.technion.ac.il.Tomer Shlomi, PhDDepartment of Computer Science, TechnionEmail: tomersh@cs.technion.ac.ilHomepage: www.cs.technion.ac.il/~tomersh

Workshop on bioprocess technology

Three-Day Workshop on “Bioprocess Technology”14 — 16 September 2009 AtBirla Institute of Scientific Research, Jaipur Birla Institute of Scientific Research, Jaipur is organizing a three-day workshop-cum-training on “Bioprocess Technology” from 14 -16 September 2009. BISR is known for providing a high quality training in advance area of Biotechnology and Bioinformatics. The focus of the current workshop is to provide participants with a guided practical training in Bioprocess Technology and will expose participants with various aspects of Bioreactors. It includes some lectures and exhaustive laboratory exposure on different aspects of microbial physiology, biochemistry and bioreactor design. The course is designed in such a way that both undergraduate and post graduate students of different areas of Life Sciences can be benefited. The laboratory includes: · Sterility techniques· Growth kinetics · Optimization of biomass accumulation· Kinetics of substrate utilization and product formation · Bioreactor operation at optimal condition The participants of the course may be students, research scholars, and Faculty member and industry personnel with background in Biotechnology and Biosciences. A certificate of attendance for Professional Development will be given to each participant who completes the course. Interested candidates may apply by sending filled application form along with the DD of Rs 2000/- latest by September 10, 2009 to the Convener, Bioprocess Technology Workshop, Birla Institute of Scientific Research, Statue Circle, Jaipur-302001. List of selected participants will be displayed on the website. The brochure and application form may be downloaded from the institute’s website at http://www.bisr.res.in/bioinfo/workshop_bioprocess.php For any query write to convener at nigam.bisr@gmail.com or training.bisr@gmail.com Dr. Vinod NigamConvener

Job Opportunities @ The Genome Center [Washington University in St. Louis]

Washington University and The Genome Center offer a pleasant, stimulating and dynamic working environment for the individual interested in the new frontier of genome biology and its expanding role in the future of clinical medicine.

Current Job Opportunities
Programmer / Bioanalyst
Programmer Analyst / Bioinformatician
Staff Scientist
Software Developer
Staff Scientist / Postdoc in Comparative Genomics
Computational Biologist
Programmer Analyst
Please Visit the above links for more details about the post

Courtesy: Washington University

Postdoctoral position : School of Biological Sciences, University of Hong Kong

School of Biological Sciences/ The Swire Institute of Marine ScienceThe University of Hong Kong
A postdoctoral position is available to study larval response to climate change, ocean acidification and emerging new pollutants at biochemical and molecular levels using environmental proteomics and/or bionanotechnology tools in economically important marine invertebrates (e.g. oyster and biofouling species).
Requirements: We are seeking talented, enthusiastic and creative young researchers with a strong commitment to interdisciplinary research. Excellent communication skills (in English), both oral and written, are essential. Previous research experience and research publication in larval culture or oyster culture, or proteomics or bionanotechnology fields are advantageous.
Qualifications: The candidate should have a Ph.D degree in marine science or marine chemistry or bionanotechnology. Research experience in calcification mechanisms, ocean acidification effects, and biominerlization is desirable. Expertise in oyster larval biology is highly encouraged to apply.
Salary: Depends on the candidates qualification and is determined by the University and the supervisor. It ranges from HK$ 14000 to 25000 per month (1 US$ = 7.8 HK$). For this salary range, the income tax is negligible in Hong Kong.
For further information about HKU please visit www.hku.hk. The HKU is ranking at 26 among the top 200 universities in the world. My environmental proteomics, ocean acidification, and larval biology laboratories are member of the School of Biological Sciences (www.hku.hk/biosch/) and the Swire Institute of Marine Science (www.hku.hk/swims/), the latter is a unique research facility situated within Hong Kong’s only Marine Reserve. As such postdoctoral fellows will be exposed to a diverse, vibrant and interdisciplinary research environment (marine molecular ecology) and will be working on one of the hot-science topics, climate change, ocean acidification and bionanotechnology.
Please send CV, a statement outlining your interests, career objectives and experience (with evidence) in marine science together with names and contact information for three references familiar with your research work. to Dr. V Thiyagarajan (rajan {at} hkucc.hku(.)hk ). Further details about our laboratory interests and research facilities can be obtained from www.hku.hk/biosch/staff/rajan/rajan.htm
courtesy: sciencejobs.com

Research Associate in Protein Crystallography at King’s College London

Applications are invited for the position of Research Associate to conduct original and high quality research to elucidate mechanisms of IgE in allergy.
The successful candidate will join the Asthma and Allergy Group, in the Randall Division of Cell and Molecular Biophysics (www.kcl.ac.uk/schools/biohealth/research/randall/). The Randall Division is located in new and well-equipped laboratories in New Hunt’s House on the Guy’s Campus of King’s College London. The Asthma and Allergy Group also participate in the Division of Allergy, Asthma and Lung Biology and the MRC & Asthma UK Centre in Allergic Mechanisms of Asthma.
A PhD in a relevant field and experience of protein crystallisation, X-ray data collection, processing, structure determination and crystallographic refinement are essential.
This post is funded for 2 years from October 2009.
Salary will be offered on grade 6, currently ranging from £32,917 – £35,755 per annum, inclusive of £2,323 London allowance per annum, depending on individual skills and experience.
For informal enquiries please contact Prof. Brian Sutton brian.sutton {at} kcl.ac(.)uk or Dr Andrew Beavil andrew.beavil {at} kcl.ac(.)uk
Further details and application packs are available on the College’s website at www.kcl.ac.uk/jobs or by emailing hsrecruit4 {at} kcl.ac(.)uk
Please quote reference number W6/JKA/298/09-DB on all correspondence.
Closing date: 09 September 2009
courtesy:sciencejobs.com

2 PhD positions at University of Copenhagen, Copenhagen, Denmark

Two PhD positions are available in the field of 3D protein structure prediction at the Bioinformatics Center, Department of Biology, University of Copenhagen, Denmark, in the group of Thomas Hamelryck (structural bioinformatics group). The positions are funded by the Danish Agency for Science, Technology and Innovation. The positions are part of a project that aims at developing novel methods to determine the structure of protein ensembles. These methods will be applied to alpha-synuclein, a protein that plays an important role in Parkinson\'s disease, and for which unique in-house data is available. The projects are built around probabilistic models of protein structure that were developed in the group (see PLoS Comput. Biol., 2006, vol. 2, issue 9, e131 and PNAS, 2008, vol. 105, 8932-8937). The students will be added to a group consisting of 4 PhD students, 2 postdocs, and a group leader, and will interact with several collaborators within Denmark and abroad (Bente Vestergaard, KU-FARMA, Jesper Ferkinghoff-Borg, DTU and Kanti Mardia, University of Leeds, UK). The employment is at the Department of Biology, The University of Copenhagen, which is located in the new Copenhagen Biocenter. The Bioinformatics Center, headed by Prof. Anders Krogh, employs around 30 scientists (including PhD students) and focuses on non-coding RNA, eukaryotic gene regulation, protein structure prediction and comparative genomics. The center provides a modern, pleasant, international working environment close to the heart of Copenhagen. Further information can be obtained from group leader Thomas Hamelryck (thamelry@binf.ku.dk ). Candidates must have a masters degree in physics, mathematics, computer science, bioinformatics, or a related relevant subject. Candidates ideally have programming experience in C or C++. Experience with the Python programming language, protein structure, machine learning or Bayesian statistics is a strong plus. The application must contain: • Curriculum vitae (incl. the applicants email address) • List of publications (if any) • Transcript of university examinations • Contact details of 2 persons for references An assessment committee will evaluate the applications. The applicant will be notified of the composition of the committee. Each applicant will receive the part of the evaluation that concerns her/him. The main criterion for selection will be the research potential of the applicant. The successful applicant will be enrolled as a PhD student at the Faculty of Science, University of Copenhagen for the 3-year duration of the PhD program. Information about the PhD programs at the Faculty of Science can be found at http://www.science.ku.dk/phd. Terms of appointment and payment are in accordance with the agreement between the Danish Ministry of Finance and the Danish Federation of Professional Associations (AC). The post is covered by the protocol on job Structure. The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background. Applications should be e-mailed as one pdf-file marked “PhD stipend in protein structure prediction” to job@bio.ku.dk . Deadline for applications is September 30, 2009 at 12:00 noon. Applications received after the deadline will not be considered.
this is a very good opportunity for those who are interested inprotein studies. i know for a fact that the bioinformatics faculty inthe univ of copenhagen is extremely good and one of the best.good luckto those who apply

7th Georgia Tech - ORNL Conference on Bioinformatics

CALL FOR PAPERS
Dear Colleagues
The 7th Georgia Tech - ORNL Conference on Bioinformatics - In silico Biology: Genome Biology and Bioinformatics will be held in Atlanta, Georgia, November 12-14, 2009 http://www2.isye.gatech.edu/binf2009/
Georgia Tech continues the tradition of organizing bi-annual International Conference on Bioinformatics, bringing together leading researchers in genomics, bioinformatics and genome biology to present recent advances in the field and to discuss open problems.
Important Dates Deadline for early registration: October 15, 2009 Deadline for poster abstract subsmission: October 1, 2009 Notification of acceptance of abstracts: October 11, 2009
We invite papers submissions in the following areas * genomics; * transcriptomics; * proteomics; * reconstruction and modeling of gene networks; * evolutionary biology;
SPEAKERS
Margaret O. Dayhoff lecture David Lipman , NCBI/NIH, Bethesda, MD, USA
Plenary Speakers: Vineet Bafna, University of California at San Diego, USA Gill Bejerano, Stanford University, Stanford, CA, USA Jeffrey Bennetzen, University of Georgia, Athens, GA, USA Mark Borodovsky, Georgia Tech and Emory University, Atlanta, GA, USA Nick Grishin, University of Texas, Dallas, TX, USA Curtis Huttenhower, Harvard University, Boston, MA, USA King Jordan, Georgia Tech, Atlanta, GA, USA Igor Jouline (Zhulin), University of Tennessee - ORNL, Oak Ridge, TN, USA Eugene Koonin, NCBI/NIH, Bethesda, MD, USA Nikos Kyrpides, DOE Joint Genome Institute, Walnut Creek, CA, USA Boris Lenhard, University of Bergen, Norway Jian Ma, University of Illinois at Urbana Champaign, Urbana, IL, USA Yael Mandel-Gutfreund, Technion, Israel Insitute of Technology, Haifa, Israel Joanna Masel, University of Arizona, Tucson, AZ, USA Andrey Mironov, Moscow State University, Russia Andrei Osterman, Burnham Institute for Medical Research, La Jolla, CA USA Karen Nelson, J. Craig Venter Institute, Rockville, MD, USA Natasa Przulj, University of California at Irvine, CA, USA John Reinitz, State Uiversity of New York at Stony Brook, NY, USA Pierre Rouze, Gent University, Gent, Belgium
CONFERENCE CHAIRS Mark Borodovsky, Georgia Tech and Emory University Eva K. Lee, Georgia Tech and Emory University
PROGRAM COMMITTEE Nicholas Bergman, Georgia Tech Dmitrij Frishman, Munich Polytechnic University, Germany Andrey Gorin, Oak Ridge National Laboratory Andrzej M. Kierzek, University of Surrey, UK. Eileen Kraemer, University of Georgia Jun Liu, Harvard University Andrey Rzhetsky, University of Chicago Andre Rogatko, Samuel Oschin Comprehensive Cancer Institute Gary Stormo, Washington University Ying Xu, University of Georgia and Oak Ridge National Laboratory Soojin Yi, Georgia Tech Igor Zhulin, Oak Ridge National Laboratory and University of Tennessee
ADMINISTRATION Harry Sharp, Georgia Tech
CONFERENCE LOCATION The Georgia Tech Ferst Center for the Arts. The Georgia Tech campus is located in Midtown Atlanta near the center of the 1996 Olympic development, close to the Fox Theatre and Margaret Mitchell house.

For further detail link to http://groups.google.co.in/group/bionet.biology.computational/browse_thread/thread/10834601adeab71e
Courtsey: bionet

Bioinformatics for Systems Biology, October 2009 Options

The distance course, Bioinformatics for Systems Biology, from The University of Manchester, will begin again on 5 October 2009. Designed to provide professional development for those in full-time employment, the course runs over 16 teaching weeks.
Teaching and learning are focussed around tutor-supported individual and group exercises. In this course, participants discuss a tutorial problem for each section of the course, and then submit solutions for feedback from the course tutor.
Week 1 Introduction to the course Installation of software for network analysis
Weeks 2 and 3 Molecular networks in biology Group discussion of models and modelling
Weeks 4 and 5 Standards for Systems Biology Data sources and standards for network biology Practical exploration of a molecular network
Weeks 6 and 7 Network properties Practical exercise on network statistics
Weeks 8 and 9 Mapping microarray data to a network
Weeks 10 and 11 Independent work on network analysis
Weeks 12 and 13 Dynamic models Further work on modelling formalisms Practical exercise on a metabolic model
Weeks 14 to 16 Independent research for the second assessment
You will find further information here : http://octette.cs.man.ac.uk/bioinformatics/modules/BIOL61820.html and the course application form is here : https://elearn.cs.man.ac.uk/sts-tng/enrol.cgi

courtsey : bionet

JOBS: Full time regular job at BROAD INSTITUTE

Job Title
Requisition Number
Area of Interest
Position Type
Associate Computational Biologist - GSAP
70
Computational Biology
Full Time - Regular
Computational Biologist - Cancer Program
34
Computational Biology
Full Time - Regular
Computational Biologist - Cancer Program
60
Computational Biology
Full Time - Regular
Computational Biologist - Genome Research
103
Computational Biology
Full Time - Regular
Group Leader, Chemical Biologist Data Analyst
75
Computational Biology
Full Time - Regular

Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways

Kaposi's sarcoma (KS), hemangioma, and other angioproliferative diseases are highly prevalent in HIV-infected individuals. While KS is etiologically linked to the human herpesvirus-8 (HHV8) infection, HIV-patients without HHV-8 and those infected with unrelated viruses also develop angiopathies.Further, HIV-Tat can activate protein-tyrosine-kinase (PTK-activity) of the vascular endothelial growth factor receptor involved in stimulating angiogenic processes. However, Tat by itself or HHV8-genes alone cannot induce angiogenesis in vivo unless specific proteins/enzymes are produced synchronously by different cell-types.We therefore tested a hypothesis that chronic HIV-replication in non-endothelial cells may produce novel factors that provoke angiogenic pathways.Methods: Genome-wide proteins from HIV-infected and uninfected T-lymphocytes were tested by subtractive proteomics analyses at various stages of virus and cell growth in vitro over a period of two years. Several thousand differentially regulated proteins were identified by mass spectrometry (MS) and >200 proteins were confirmed in multiple gels.Each protein was scrutinized extensively by protein-interaction-pathways, bioinformatics, and statistical analyses.Results: By functional categorization, 31 proteins were identified to be associated with various signaling events involved in angiogenesis. 88% proteins were located in the plasma membrane or extracellular matrix and >90% were found to be essential for regeneration, neovascularization and angiogenic processes during embryonic development.Conclusion: Chronic HIV-infection of T-cells produces membrane receptor-PTKs, serine-threonine kinases, growth factors, adhesion molecules and many diffusible signaling proteins that have not been previously reported in HIV-infected cells.Each protein has been associated with endothelial cell-growth, morphogenesis, sprouting, microvessel-formation and other biological processes involved in angiogenesis (p =10-4 to 10-12). Bioinformatics analyses suggest that overproduction of PTKs and other kinases in HIV-infected cells has suppressed VEGF/VEGFR-PTK expression and promoted VEGFR-independent pathways.
This unique mechanism is similar to that observed in neovascularization and angiogenesis during embryogenesis. Validation of clinically relevant proteins by gene-silencing and translational studies in vivo would identify specific targets that can be used for early diagnosis of angiogenic disorders and future development of inhibitors of angiopathies.This is the first comprehensive study to demonstrate that HIV-infection alone, without any co-infection or treatment, can induce numerous "embryonic"proteins and kinases capable of generating novel VEGF-independent angiogenic pathways.courtesy:
Author: Suraiya RasheedJasper YanAdil HussainBruce Lai

40 posts are vacant at NIN,Hyderabad | B.Sc, M.Sc, PhD Life sciences | Salary Upto 30,000/- Rs

Eligible candidates are invited to attend a WALK-IN-INTERVIEW for the following posts on the ad hoc research project entitled “Nutritive value of Indian Foods”- “Integrated Indian Food Composition Tables” on the following dates mentioned against the posts and category. Depending upon the number of candidates Written Examination/Interview will be conducted. The essential qualification, experience, consolidated salary and service tenure are as under. All candidates should report by 9:30 A.M. sharply on the specified dates of interview for the respective post for scrutiny of certificates and test/ interview.
Position: Lab/Field Manager (4 seats)Qualification: M.Sc.1st Class/ M.Sc. with Ph.D. in Biochemistry/ Life science with three years relevant laboratory experience.Desirable: Conversant with the handling of either of the instruments UPLC/ HPLC/ ICPMS/ LCMS/ AAS/ Dumas nitrogen analyzer/ amino acid analyzer. Minimum one to three years experience.Age: 35 years. Relaxation in case of SC/ ST/ OBC/ PH candidates as per G.O.I. Rules.Salary: Rs 30,000/-p.m. (Fixed) without any allowancesDate Of Interview: 14-09-2009
Position: Technical Assistant (36 seats)Qualification: B.Sc. with Chemistry and Biology as one of the subject.Desirable: M.Sc. in Chemistry/Biochemistry/Zoology/ Botany/Microbiology/Food science/Food Science & Nutrition with experience in analysis of nutrients in foods. Experience in handling of UPLC/ HPLC/ ICPMS/ LCMS/ AAS/ kjeldahl nitrogen analyzer, microwave ashing system, microwave digestion system, muffle furnace, Satboiling distillation system will be an added advantage. Minimum one to three years experience.Age: 28 years. Relaxation in case of SC/ ST/ OBC/ PH candidates as per G.O.I. Rules.Salary: Rs. 10,835/-p.m. (Fixed) without any allowances.Date Of Interview: 17-09-2009
Tenure: The Tenure for all the above posts is 4 years. Initially the appointment will be given for a period of one year and extendable based on the performance.
The candidates should bring all original certificates of educational qualification (from SSC onwards), experience and caste along with a photo and set of Xerox copies duly attested while attending the Walk-in-Interview. The persons belongs to Other Backward Category should bring the O.B.C. Certificate issued by the respective concerned Thehsildar/ M.R.O.'s specifically issued for the purpose of applying for Central Government post. No TA/DA will be paid for attending the Interviews.
GENERAL CONDITIONS: The conditions of employment will be the same as are for the project staff on contract basis. The job involves extensive touring all over the country as and when required besides the normal laboratory duties. Only those who are willing and able to travel extensively only need apply. The candidates have no right to claim for any regular employment at this Institute. The Director & Appointing Authority has the right to accept / reject any application without assigning any reason and no correspondence in this matter will be entertained.
NATIONAL INSTITUTE OF NUTRITIONIndian Council of Medical ResearchTarnaka, JAMAI-OSMANIA, HYDERABAD – 500 007.
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SRF post at Microbiology Division, IARI, New Delhi | M.Sc Bio Sciences can apply

A walk-in-interview for filling up the following temporary position of Sr. Research Fellow (1 SRF) in ICAR-NAIP project will be held on 18.09.2009 at 9.30 A.M. in Room No. 1, Division of Microbiology, IARI, New Delhi-110012 (Tel. No. 011-25847649).
Project Title: Diversity analysis of Bacillus and other predominant genera in extreme environments and its utilization in AgriculturePI: Dr. A.K. SaxenaQualification: M.Sc. in Microbiology/Biotechnology/Botany with specialization in Bacteriology.Desirable: Research Experience in molecular characterization of microbes knowledge of computer and bioinformatics tools.Salary: Rs.12,000/- + 30% HRA
Terms and Conditions:1.Maximum age limit is 35 years (Age relaxation for SC/ST/OBC women candidates as per GOI norms).2.No objection and experience certificate from the employer in case he/she is in employment.3.Positions are purely temporary and co-terminus with the project, initially for a period of one year. Selected candidates will not be entitled to claim for regular appointments/absorption either in this institute or ICAR.4.No TA/DA will be paid for attending the interview.5.Candidates may appear for walk-in-interview with bio-data, photographs and original testimonials.6.Candidates reaching after specified timing will not be entertained.7.Canvassing in any form will disqualify the candidature. The Director’s decision will be final and binding in all respect.8.Candidates may send their bio-data (Hard copy) in advance to Dr. A.K. Saxena, Head, Division of Microbiology, IARI, New Delhi-110012 (saxena461@yahoo.com) preferable before 12-09-2009.
View Original Notification

SRF posts at NIT,Durgapur | ME/M.Tech/M.Sc's can earn Rs 19500/-

Applications are invited from suitable candidates for a position of Senior Research Fellow under a DST-Govt.of India-funded project entitled ‘Production of Lactic acid in membrane-integrated hybrid reactor system- A green technology approach’ under the guidance of Prof.P.Pal.Position: Senior Research FellowAd No: NITD/ ChE/DST-SERC/GC/2009/1Qualification: M.E./M.Tech. in Chemical Engineering/ Bio-chemical Engineering/ Bio-Technology/Environmental Engineering/ or Masters Degree in Biotechnology/ Pharmacy/ Environmental Science/ Bio-informatics with strong computational capability. GATE-qualified candidates will get preference. Candidates appearing in the qualifying examination in 2009 and expecting final results shortly may also apply, however, their appointment may be provisional subject to satisfying minimum qualification within one month of selection.Fellowship: Rs.15000/ p.m. + HRA @Rs.4500/ p.m. Total Rs. 19,500/- p.m.(consolidated)for M.E./M.Tech and for others as per relevant DST norms.Duration: 3 years, Candidates joining as SRF may register for Ph.D. work under the same guide.
How to Apply: Candidates should apply in plain paper giving 1) Name & address (including e-mail address,2)Telephone/mobile phone number 3) Academic qualifications from 10+ onwards ( giving Institute name, year of passing, % marks, class ) 4) Any special training/experience 5) Names of two referees with phone numbers 5) attested copies of all mark sheets/certificates. Complete applications should reach the address given below latest by 20th September 2009.
Address for sending applications: Professor Parimal Pal Department of Chemical EngineeringNational Institute of Technology DurgapurWest Bengal-713209The short-listed candidates will be informed through e-mail/phone for appearing before a selection committee at N.I.T. Durgapur. No TA/DA will be paid to the candidates for appearing before the selection committee.View Original Notification

M.Tech Biotech can apply for JRF post at ICT,Mumbai | Salary upto Rs 15000/-

Application are invited from Indian nationals for the position of one junior research fellow (extended to senior research fellow in third year) scheme entitled “Structure based Drug Design of DHFR inhibitors as Anti-tubercular Agents” Sponsored by Department of Biotechnology (DBT), Government of India.Position: JRF converted to SRF after 1 year.Duration: 2 yearsQualification: M.Pharm. / M. Tech (Pharma / Biotech)Desirable: Candidates having experience in CADD based design or experimental evaluation of NCE’s cell based/enzyme assays would be preferred. Research assistance is subject to continuation of the project and satisfactory performance of the candidate. Salary: Rs. 14,000/- plus HRA per month for the first one year and Rs. 15,000/- plus HRA for second year.Applications should be submitted to Ms. Vipula D. Kulkarni, Director’s Office along with the necessary certificates before 7th September 2009. The envelope containing the application should be marked DBT Research Project / MSD.Selected candidate may be allowed to register for PhD (Tech.) degree as per rules of ICT. Candidates called for interview will not be given TA/DA.
Institute of Chemical TechnologyMatunga, Mumbai - 400 019
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Become a Post Doc Fellow at Novo Nordisk Centre for Protein Research,Copenhagen

The Novo Nordisk Foundation Center for Protein Research (CPR) is recently being established at the Faculty of Health Sciences, University of Copenhagen, to promote basic and applied discovery research on human proteins of medical relevance (www.cpr.ku.dk). The establishment of the Center has been made possible by a large donation from the Novo Nordisk Foundation.
Qualifications: Candidates are required to have a PhD obtained within recent years in a relevant biological area. Strong motivation and excellent scientific skills are essential.
Desirable: Documented experience with tissue cell culture, gene cloning and general immunological and protein chemistry techniques is also required. Knowledge in cell signaling and confocal microscopy specifically applied to the study of liver would be considered a distinct advantage. Prior experience working with in vivo models is desirable. An analytical aptitude of devising innovative scientific or technical solutions Good communication skills, both oral and written.Employment Conditions: Employment will be in accordance with the provisions of the collective agreement between the Danish Government and AC (the Danish Confederation of Professional Associations). The position will be at the level of post doc, and you will be placed in salary group 6 with the possibility to negotiate a supplement. To the basic salary is added a monthly contribution to a pension fund (17.1% of the salary). The ability to perform the job will be the primary consideration for selecting the candidate, and thus we encourage all – regardless of their personal background and status - to apply. The tentative start date is 1 September 2009 or shortly after.
ApplicationFor further information, please contact Group Leader Amilcar Flores-Morales by e-mail Amilcar.Flores@ki.se,Your application marked “211-0029/09-3850 Postdoctoral Disease Biology” including a CV and degree as well as names and contact details of referees must be sent to the NNF Center for Protein Research before 7 September 2009. Your application should be sent as a single document by e-mail to jobs@cpr.ku.dk.
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