[bioinfo] PhD position in evolutionary genomics, Lausanne, Switzerland]

PHD IN FUNCTIONAL EVOLUTIONARY GENOMICSCenter for Integrative Genomics, University of Lausanne, SwitzerlandA PhD student position (~4 years) is available in the evolutionarygenomics group of Henrik Kaessmann in the framework of major newprojects funded by the European Research Council.We are seeking talented and highly motivated applicants (preferably withsome experience/background in molecular evolution), who have strongprogramming skills (or the willingness and drive to acquire them) and aninterest in evolutionary genome analyses using bioinformaticsapproaches. A MSc degree or equivalent is required.Our group has been interested in a range of topics related to thefunctional evolution of genomes from primates (e.g., emergence of newgenes and their functions) and other mammals (e.g., the origin andevolution of mammalian sex chromosomes). In the framework of a new majorline of projects funded by the European Research Council, a large amountof qualitative and quantitative transcriptome data will be produced fora unique collection of tissues from representative mammals by the wetlab unit of the group using next generation sequencing technologies(RNA-Seq). The PhD student will perform integratedevolutionary/bioinformatics analyses based on these data and availablemammalian genomes. The specific project will be developed together withthe candidate.The language of the institute is English, and its members form aninternational group that is rapidly expanding. The institute is locatedin Lausanne, a beautiful city at Lake Geneva.For more information on the group and our institute more generally,please refer to our website: http://www.unil.ch/cig/page7858_en.html
Please submit a CV, statement of research interest, and names of threereferences to: Henrik Kaessmann (Henrik.Kaessmann@unil.ch).--Henrik Kaessmann, Ph.D.Associate ProfessorCenter for Integrative GenomicsUniversity of Lausanne, SwitzerlandE-mail: Henrik.Kaessmann@unil.chPhone: +41 (0)21 692 3960Some recent publications from the lab:Henrichsen, C., Vinckenbosch, N., Zöllner, S., Chaignat, E., Pradervand,S., Frédéric Schütz, Ruedi, M., *Kaessmann, H. and *Reymond, A. (2009)Segmental copy number variation shapes tissue transcriptomes. NatureGenet. 41: 429-9.Potrzebowski, L., Vinckenbosch, N., Marques, A. C., Chalmel, F., Jegou,B. & Kaessmann, H. (2008) Chromosomal Gene Movements Reflect the RecentOrigin and Biology of Therian Sex Chromosomes. PLoS Biol. 6: e80.Brawand, D., Wahli, W. & Kaessmann, H. (2008) Loss of egg yolk genes inmammals and the origin of lactation and placentation. PLoS Biol. 6: e63.Rosso, L., Marques, A. C., Weier, M., Lambert, N., Lambot, M.-A.,Vanderhaeghen, P. & Kaessmann, H. (2008) Birth and Rapid SubcellularAdaptation of a Hominoid-Specific CDC14 Protein. PLoS Biol. 6: e140.Vinckenbosch, N., Dupanloup, I. & Kaessmann, H. (2006) Evolutionary fateof retroposed gene copies in the human genome. Proc. Natl. Acad. Sci. U.S. A. 103: 3220-3225.Marques, A., Dupanloup, I., Vinckenbosch, N., Reymond, A. & Kaessmann,H. (2005) Emergence of young human genes after a burst of retropositionin primates. PLoS Biol. 3: e357.Burki, F. & Kaessmann, H. (2004) Birth and adaptive evolution of ahominoid gene supporting high neurotransmitter flux. Nature Genet. 10:
1061-1063.--Magali Michaut, PhDhttp://baderlab.org/MagaliMichaut